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Hudak, S.K.* ; Overkamp, D.* ; Wagner, R.* ; Häring, H.-U. ; Heni, M.

Ketoacidosis in a non-diabetic woman who was fasting during lactation.

Nutr. J. 14:117 (2015)
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Ketoacidosis is a potential complication of type 1 diabetes. Severe ketoacidosis with a blood pH below 7.0 is only rarely seen in other diseases.Three weeks after delivery, a young woman was admitted because of tachypnoe and tachycardia. Blood gas analysis showed a severe metabolic acidosis with a high anion gap. Further workup revealed the presence of ketone bodies in the urine with normal blood glucose and no history of diabetes. The patient reported that she had not eaten for days because of abdominal pain. After initial treatment in the ICU and immediate re-feeding, the patient's condition rapidly improved.While under normal circumstances fasting causes at most only mild acidosis, it can be dangerous during lactation. Prolonged fasting in combination with different forms of stress puts breast feeding women at risk for starvation ketoacidosis and should therefore be avoided.
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Publication type Article: Journal article
Document type Scientific Article
Language english
Publication Year 2015
HGF-reported in Year 2015
ISSN (print) / ISBN 1475-2891
Journal Nutrition Journal
Quellenangaben Volume: 14, Issue: 1, Pages: , Article Number: 117 Supplement: ,
Publisher BioMed Central
Publishing Place London
Reviewing status Peer reviewed
Institute(s) Institute of Diabetes Research and Metabolic Diseases (IDM)
POF-Topic(s) 90000 - German Center for Diabetes Research
Research field(s) Helmholtz Diabetes Center
PSP Element(s) G-502400-001
PubMed ID 26537818
DOI 10.1186/s12937-015-0076-2
WOS ID WOS:000364381800001
Erfassungsdatum 2015-12-03
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