Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
DOI
 |
|
Open Access Green as soon as Postprint is submitted to ZB.
Biological monitoring of welders exposed to aluminium.
Toxicol. Lett. 162, 239-245 (2006)
To evaluate an adequate strategy for biological monitoring of aluminium (Al), a group of 62 Al welders (age in 1999: 23-51 years, median 35 years) was surveyed annually from 1999 to 2003 by determination of pre- and post-shift Al in urine and plasma. Biomonitoring was supplemented by personal air measurements of the total dust concentration. The welders' internal exposure was compared to the exposure of 60 non-exposed assembly workers (age in 1999: 21-51 years, median: 36 years) who were surveyed in 1999, 2001 and 2003. Having a nearly constant dust exposure, median concentrations of Al in urine (Al in plasma) of the welders decreased from 40.1 μg/g to 19.8 μg/g creatinine (8.7 to 4.6 μg/l). For the control group the median levels of Al in urine (plasma) ranged from 4.8 μg/g to 5.2 μg/g creatinine (2.4-4.3 μg/l) indicating a higher sensitivity for the marker Al in urine. No systematic differences have been found between pre- and post-shift internal exposure. This might be caused by the slow elimination kinetics and low systemic bioavailability of Al. A correlation analysis did not yield close relationships between dust exposure, Al in plasma and Al in urine underlining the importance of biomonitoring for assessment of Al exposure. © 2005 Elsevier Ireland Ltd. All rights reserved.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Scientific Article
Keywords
aluminium; aluminium welders; biomonitoring; welding fumes
ISSN (print) / ISBN
0378-4274
e-ISSN
1879-3169
Journal
Toxicology Letters
Quellenangaben
Volume: 162,
Issue: 2-3,
Pages: 239-245
Publisher
Elsevier
Publishing Place
Amsterdam
Non-patent literature
Publications
Reviewing status
Peer reviewed