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Assays for the expression and release of insulin and glucose-regulating peptide hormones from pancreatic β-cell.
In: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 3029-3057
The in vitro perfusion of the isolated rat pancreas as described by Anderson and Long (1947), Ross (1972), Grodsky and coworkers (1983, 1984), and Muñoz and coworkers (1995) offers the advantage to study the influence of carbohydrates, hormones, and drugs such as sulfonylureas not only on insulin but also on glucagon and somatostatin secretion without interference of secondary effects resulting from changes in hepatic, pituitary, or adrenal functions.
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Publication type
Article: Edited volume or book chapter
Editors
Hock, F.J.*
Language
english
Publication Year
2016
HGF-reported in Year
2016
e-ISSN
978-3-319-05392-9
ISBN
978-3-319-05391-2
Book Volume Title
Drug Discovery and Evaluation: Pharmacological Assays
Quellenangaben
Pages: 3029-3057
Publisher
Springer
Publishing Place
Cham, Switzerland
Institute(s)
Institute of Diabetes and Obesity (IDO)
POF-Topic(s)
30201 - Metabolic Health
Research field(s)
Helmholtz Diabetes Center
PSP Element(s)
G-502200-001
Scopus ID
84957673698
Erfassungsdatum
2016-02-20