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Müller, G.

Assays for the expression and release of insulin and glucose-regulating peptide hormones from pancreatic β-cell.

In: Drug Discovery and Evaluation: Pharmacological Assays. Cham, Switzerland: Springer, 2016. 3029-3057

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The in vitro perfusion of the isolated rat pancreas as described by Anderson and Long (1947), Ross (1972), Grodsky and coworkers (1983, 1984), and Muñoz and coworkers (1995) offers the advantage to study the influence of carbohydrates, hormones, and drugs such as sulfonylureas not only on insulin but also on glucagon and somatostatin secretion without interference of secondary effects resulting from changes in hepatic, pituitary, or adrenal functions.

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Publication type Article: Edited volume or book chapter

Editors Hock, F.J.*

Corresponding Author

e-ISSN 978-3-319-05392-9

ISBN 978-3-319-05391-2

Book Volume Title Drug Discovery and Evaluation: Pharmacological Assays

Quellenangaben Pages: 3029-3057

Publisher Springer

Publishing Place Cham, Switzerland

Non-patent literature Publications

Institute(s) Institute of Diabetes and Obesity (IDO)