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Combs, S.E. ; Nüsslin, F.* ; Wilkens, J.J.

Individualized radiotherapy by combining high-end irradiation and magnetic resonance imaging.

Individualisierte Strahlentherapie durch Kombination von „High-end“-Bestrahlung und Magnetresonanzbildgebung.

Strahlenther. Onkol. 192, 209-215 (2016)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
Image-guided radiotherapy (IGRT) has been integrated into daily clinical routine and can today be considered the standard especially with high-dose radiotherapy. Currently imaging is based on MV- or kV-CT, which has clear limitations especially in soft-tissue contrast. Thus, combination of magnetic resonance (MR) imaging and high-end radiotherapy opens a new horizon. The intricate technical properties of MR imagers pose a challenge to technology when combined with radiation technology. Several solutions that are almost ready for routine clinical application have been developed. The clinical questions include dose-escalation strategies, monitoring of changes during treatment as well as imaging without additional radiation exposure during treatment.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Image-guided Radiotherapy ; Individualized Medicine ; Magnetic Resonance-guided Radiotherapy ; Organ Sparing Treatments ; Organs At Risk; Advanced Pancreatic-cancer; Guided Radiation-therapy; Target Volume Definition; Low-grade Astrocytomas; Normal Brain-tissue; Rectal-cancer; Dose-escalation; Neoadjuvant Chemoradiation; Esophagogastric Junction; Glioblastoma-multiforme
ISSN (print) / ISBN 0179-7158
e-ISSN 1439-099X
Quellenangaben Volume: 192, Issue: 4, Pages: 209-215 Article Number: , Supplement: ,
Publisher Urban & Vogel
Publishing Place Munich
Non-patent literature Publications
Reviewing status Peer reviewed