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Seeka, C.* ; Sutthivaiyakit, P.* ; Youkwan, J.* ; Hertkorn, N. ; Harir, M. ; Schmitt-Kopplin, P. ; Sutthivaiyakit, S.*

Prenylfuranocoumarin-HMGA-flavonol glucoside conjugates and other constituents of the fruit peels of Citrus hystrix and their anticholinesterase activity.

Phytochemistry 127, 38-49 (2016)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Sixteen compounds including dihydroxy prenylfuranocoumarins/3-hydroxy-3-methylglutaric acid conjugates and dihydroxy prenylfuranocoumarins/3-hydroxy-3-methylglutaric acid/1-O-flavonyl-β-d-glucopyranoside conjugates, together with other dihydroxyprenylfuranocoumarins conjugates, were isolated from the ethyl acetate extract of the fruit peels of Citrus hystrix. Some of the isolates were evaluated for their cholinesterase inhibitory activity, but only one compound possessing a 3-O-β-d-glucopyranosyl-3,5,7,4'-tetrahydroxy-6,8,3'-trimethoxyflavonol nucleus in the prenylfuranocoumarin-HMGA conjugate showed strong activity.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Anticholinesterase Activity ; Citrus Hystrix ; Flavonol Glucosides ; Hydroxymethyl Glutaric Acid (hmga) Ester ; Prenylfuranocoumarins ; Rutaceae; Raw 264.7 Cells; Absolute-configuration; Glycosides; Coumarins; Derivatives; Generation; Inhibitors; Roots; Alkyl; Acid
ISSN (print) / ISBN 0031-9422
e-ISSN 1873-3700
Journal Phytochemistry
Quellenangaben Volume: 127, Issue: , Pages: 38-49 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Oxford
Non-patent literature Publications
Reviewing status Peer reviewed