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Prenylfuranocoumarin-HMGA-flavonol glucoside conjugates and other constituents of the fruit peels of Citrus hystrix and their anticholinesterase activity.
Phytochemistry 127, 38-49 (2016)
Sixteen compounds including dihydroxy prenylfuranocoumarins/3-hydroxy-3-methylglutaric acid conjugates and dihydroxy prenylfuranocoumarins/3-hydroxy-3-methylglutaric acid/1-O-flavonyl-β-d-glucopyranoside conjugates, together with other dihydroxyprenylfuranocoumarins conjugates, were isolated from the ethyl acetate extract of the fruit peels of Citrus hystrix. Some of the isolates were evaluated for their cholinesterase inhibitory activity, but only one compound possessing a 3-O-β-d-glucopyranosyl-3,5,7,4'-tetrahydroxy-6,8,3'-trimethoxyflavonol nucleus in the prenylfuranocoumarin-HMGA conjugate showed strong activity.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Anticholinesterase Activity ; Citrus Hystrix ; Flavonol Glucosides ; Hydroxymethyl Glutaric Acid (hmga) Ester ; Prenylfuranocoumarins ; Rutaceae; Raw 264.7 Cells; Absolute-configuration; Glycosides; Coumarins; Derivatives; Generation; Inhibitors; Roots; Alkyl; Acid
ISSN (print) / ISBN
0031-9422
e-ISSN
1873-3700
Journal
Phytochemistry
Quellenangaben
Volume: 127,
Pages: 38-49
Publisher
Elsevier
Publishing Place
Oxford
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Research Unit Analytical BioGeoChemistry (BGC)