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Markmann, J.F.* ; Bartlett, S.T.* ; Johnson, P.* ; Korsgren, O.* ; Hering, B.J.* ; Scharp, D.* ; Kay, T.W.* ; Bromberg, J.* ; Odorico, J.S.* ; Weir, G.C.* ; Bridges, N.D.* ; Kandaswamy, R.* ; Stock, P.* ; Friend, P.* ; Gotoh, M.* ; Cooper, D.K.* ; Park, C.G.* ; OʼConnell, P.J.* ; Stäbler, C.* ; Matsumoto, S.* ; Ludwig, B. ; Choudhary, P.* ; Khovatchev, B.* ; Rickels, M.R.* ; Sykes, M.* ; Wood, K.* ; Kraemer, K.* ; Hwa, A.* ; Stanley, E.* ; Ricordi, C.* ; Zimmerman, M.* ; Greenstein, J.* ; Montanya, E.* ; Otonkoski, T.*

Executive summary of IPITA-TTS opinion leaders report on the future of β-cell replacement.

Transplantation 100, E25-E31 (2016)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
The International Pancreas and Islet Transplant Association (IPITA), in conjunction with the Transplantation Society (TTS), convened a workshop to consider the future of pancreas and islet transplantation in the context of potential competing technologies that are under development, including the artificial pancreas, transplantation tolerance, xenotransplantation, encapsulation, stem cell derived beta cells, beta cell proliferation, and endogenous regeneration. Separate workgroups for each topic and then the collective group reviewed the state of the art, hurdles to application, and proposed research agenda for each therapy that would allow widespread application. Herein we present the executive summary of this workshop that focuses on obstacles to application and the research agenda to overcome them; the full length article with detailed background for each topic is published as an online supplement to Transplantation.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Porcine Islet Xenotransplantation; Mediated Inflammatory Reaction; Nonhuman-primates; Cynomologus Monkeys; Pig Islets; Reversal; Transplantation; Survival; Immunosuppression; Autoimmunity
ISSN (print) / ISBN 0041-1337
e-ISSN 1534-0608
Journal Transplantation
Quellenangaben Volume: 100, Issue: 7, Pages: E25-E31 Article Number: , Supplement: ,
Publisher Lippincott Williams & Wilkins
Publishing Place Philadelphia
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute for Pancreatic Beta Cell Research (IPI)