Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
Postprint
PMC
 |
|
Open Access Gold as soon as Publ. Version/Full Text is submitted to ZB.
Aorta atherosclerosis lesion analysis in hyperlipidemic mice.
Bio Protoc. 6, accepted (2016)
Atherosclerosis is a chronic inflammatory disease of large and medium-sized arteries. Apolipoprotein E-deficient (ApoE(-/-)) mice are used as experimental models to study human atherosclerosis. ApoE(-/-) mice are constitutively hyperlipidemic and develop intima plaques that resemble human plaques. Various issues including experimental design for lesion analysis, dietary conditions, isolation of the aorta, staining methods, morphometry, group size, age, the location within the arterial tree, and statistical analyses are important parameters that need to be addressed to obtain robust data. Here, we provide detailed methods to quantify aorta atherosclerosis.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Scientific Article
e-ISSN
2331-8325
Journal
Bio-Protocol
Quellenangaben
Volume: 6,
Issue: 11
Publisher
bio-protocol.org
Publishing Place
Sunnyvale, CA
Reviewing status
Peer reviewed
Institute(s)
Research Unit Molecular Immune Regulation (AMIR)