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A pluripotency platform for Prdm14.
Dev. Cell 38, 3-5 (2016)
The tripartite network of Prdm14, Blimp1, and AP2γ is essential for the important process of germ cell specification, but their precise molecular mechanisms of action remain lacking. Tu and colleagues (2016) report in Nature that the transcriptional co-repressor CBFA2T2 is an essential interactor protein regulating PRDM14 function, shedding light into the mechanisms directing germline formation and pluripotency.
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Publication type
Article: Journal article
Document type
Editorial
Keywords
Germ-cell Lineage; Mice
Language
english
Publication Year
2016
HGF-reported in Year
2016
ISSN (print) / ISBN
1534-5807
e-ISSN
1878-1551
Journal
Developmental Cell
Quellenangaben
Volume: 38,
Issue: 1,
Pages: 3-5
Publisher
Elsevier
Publishing Place
Cambridge
Reviewing status
Peer reviewed
Institute(s)
Institute of Epigenetics and Stem Cells (IES)
POF-Topic(s)
30204 - Cell Programming and Repair
Research field(s)
Stem Cell and Neuroscience
PSP Element(s)
G-506200-001
WOS ID
WOS:000380073400002
Scopus ID
84979702315
PubMed ID
27404351
Erfassungsdatum
2016-07-21