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Müller, T.D. ; Tschöp, M.H. ; O'Rahilly, S.*

Metabolic precision medicines: Curing POMC deficiency.

Cell Metab. 24, 194-195 (2016)
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Pro-opiomelanocortin deficiency is a rare cause of severe intractable obesity. Two patients have experienced dramatic weight loss in response to setmelanotide, a melanocortin-4 receptor activator. The drug has potential in broader populations, but caution is warranted as it may act at other melanocortin receptors.
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Publication type Article: Journal article
Document type Editorial
Corresponding Author
Keywords Melanocortin-4 Receptor; Obesity; Humans; Leptin
ISSN (print) / ISBN 1550-4131
e-ISSN 1932-7420
Journal Cell Metabolism
Quellenangaben Volume: 24, Issue: 2, Pages: 194-195 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Cambridge
Non-patent literature Publications
Reviewing status Peer reviewed