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DNA-nanostructure-gold-nanorod hybrids for enhanced in vivo optoacoustic imaging and photothermal therapy.
Adv. Mater. 28, 10000-10007 (2016)
A functional cancer theranostic nanoplatform is developed, specifically tailored toward the optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA origami is used as an efficient delivery vehicle owing to its prominent tumor-targeting property. The D-AuNR hybrids display an enhanced tumor diagnostic sensitivity by improved optoacoustic imaging and excellent photothermal therapeutic properties in vivo.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Dna Origami ; Cancer ; Gold Nanorods ; Optoacoustic Imaging ; Photoacoustic Imaging ; Photothermal Therapy; Optical Contrast Agent; Photoacoustic Tomography; Living Mice; Cancer; Nanoparticles; Tissue; Nanomaterials; Delivery; Origami; Fluorescent
ISSN (print) / ISBN
0935-9648
e-ISSN
1521-4095
Journal
Advanced materials
Quellenangaben
Volume: 28,
Issue: 45,
Pages: 10000-10007
Publisher
Wiley
Publishing Place
Weinheim
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)