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Low-level mercury exposure and risk of Asthma in school-age children.
Epidemiology 28, 116-118 (2017)
BACKGROUND: Although mercury exposure has been associated with several adverse health effects, the association with childhood asthma is under-investigated. Therefore, we explore the association between mercury and childhood asthma in a population with low mercury levels. METHODS: Mercury levels were measured in blood and urine in 1,056 children aged 5-14 years. In addition to including questions about asthma diagnosis and wheezing, the study measured bronchial hyper-responsiveness and allergic sensitization to common aeroallergens. Logistic regression analysis adjusted for major potential confounders. RESULTS: Overall the adjusted odds ratios (aOR) between log blood mercury and the outcomes were 0.8 (95% CI 0.63, 1.11) for asthma, 0.9 (95% CI 0.79, 1.14) for wheeze, 1.1 (95% CI 0.60, 2.03) for bronchial hyperresponsiveness, and 1.0 (95% CI 0.80, 1.17) for allergic sensitization. Urine mercury adjusted for creatinine was also not associated with any of these allergy-related outcomes. CONCLUSIONS: While the results did not support an association between mercury exposure and asthma, studies are needed to assess prenatal and lifetime exposure to mercury and asthma.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Health; Germany
Language
Publication Year
2017
Prepublished in Year
2016
HGF-reported in Year
2016
ISSN (print) / ISBN
1044-3983
e-ISSN
1531-5487
Journal
Epidemiology
Quellenangaben
Volume: 28,
Issue: 1,
Pages: 116-118
Publisher
Lippincott Williams & Wilkins
Publishing Place
Philadelphia
Reviewing status
Peer reviewed
Institute(s)
Institute of Epidemiology (EPI)
POF-Topic(s)
30503 - Chronic Diseases of the Lung and Allergies
Research field(s)
Genetics and Epidemiology
PSP Element(s)
G-503900-001
WOS ID
WOS:000390252100026
PubMed ID
27755278
Erfassungsdatum
2016-10-24