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Safita, N. ; Islam, S.M.S.* ; Chow, C.K.* ; Niessen, L.W.* ; Lechner, A. ; Holle, R. ; Laxy, M.

The impact of type 2 diabetes on health related quality of life in Bangladesh: Results from a matched study comparing treated cases with non-diabetic controls.

Health Qual. Life Outcomes 14:129 (2016)
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Background: Little is known about the association between diabetes and health related quality of life (HRQL) in lower-middle income countries. This study aimed to investigate HRQL among individuals with and without diabetes in Bangladesh. Methods: The analysis is based on data of a case-control study, including 591 patients with type 2 diabetes (cases) who attended an outpatient unit of a hospital in Dhaka and 591 age -and sex-matched individuals without diabetes (controls). Information about socio-demographic characteristics, health conditions, and HRQL were assessed in a structured interview. HRQL was measured with the EuroQol (EQ) visual analogue scale (VAS) and the EQ five-dimensional (5D) descriptive system. The association between diabetes status and quality of life was examined using multiple linear and logistic regression models. Results: Mean EQ-VAS score of patients with diabetes was 11.5 points lower (95 %-CI: -13.5, -9.6) compared to controls without diabetes. Patients with diabetes were more likely to report problems in all EQ-5D dimensions than controls, with the largest effect observed in the dimensions 'self-care' (OR = 5.9; 95 %-CI: 2.9, 11.8) and 'mobility' (OR = 4. 5; 95 %-CI: 3.0, -6.6). In patients with diabetes, male gender, high education, and high-income were associated with higher VAS score and diabetes duration and foot ulcer associated with lower VAS scores. Other diabetes-related complications were not significantly associated with HRQL. Conclusions: Our findings suggest that the impact of diabetes on HRQL in the Bangladeshi population is much higher than what is known from western populations and that unlike in western populations comorbidities/complications are not the driving factor for this effect.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Diabetes ; Complications ; Quality Of Life ; Bangladesh ; Eq-5d ; Case Control Study; Nationwide Survey; Risk-factors; Complications; Population; Mellitus; Prevalence; Adults; Eq-5d; Care; Burden
Language english
Publication Year 2016
HGF-reported in Year 2016
ISSN (print) / ISBN 1477-7525
e-ISSN 1477-7525
Quellenangaben Volume: 14, Issue: , Pages: , Article Number: 129 Supplement: ,
Publisher BioMed Central
Publishing Place London
Reviewing status Peer reviewed
Institute(s) Institute of Health Economics and Health Care Management (IGM)
CCG Nutrigenomics and Type 2 Diabetes (KKG-KDN)
POF-Topic(s) 30202 - Environmental Health
90000 - German Center for Diabetes Research
Research field(s) Genetics and Epidemiology
PSP Element(s) G-505300-002
G-501900-531
G-501900-701
Scopus ID 84992058794
Erfassungsdatum 2016-10-31