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Adler, B.* ; Sattler, C. ; Adler, H.

Herpesviruses and their host cells: A successful liaison.

Trends Microbiol., DOI: 10.1016/j.tim.2016.11.009 (2016)
Postprint DOI
Open Access Green
During a long history of coevolution, herpesviruses have reached a fine-tuned balance with their hosts, allowing them to successfully persist and spread to new hosts without causing too much damage. Only under certain circumstances, as in neonates or immunocompromised individuals, they may cause serious diseases. The delicate balance between herpesviruses and their hosts results from interactions of a great variety of viral and cellular factors which together shape the tropism for a particular host, tissue, or cell. Understanding these interactions will provide insight into the viral life cycle and cell biology in general. Moreover, it will also facilitate comprehension of herpesvirus pathogenesis, enabling the development of new strategies to combat herpesviruses in cases where they cause disease.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords herpesviruses, tropism, cell and tissue types, restriction factors
ISSN (print) / ISBN 0966-842X
e-ISSN 1878-4380
Journal Trends in microbiology
Publisher Cell Press
Publishing Place Cambridge, Mass.
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Research Unit Lung Repair and Regeneration (LRR)