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Open Access Green as soon as Postprint is submitted to ZB.
Diabetes mellitus and bone metabolism.
Exp. Clin. Endocrinol. Diabet. 26, 90-94 (2017)
Diabetes mellitus and bone metabolism affect mesenchymal tissues and have numerous epidemiological and pathophysiological associations in common. Diabetes mellitus affects bone metabolism and increases fracture risk. The pathophysiological mechanims how type 1 and type 2 diabetes impair bone metabolism and bone strength may differ which is outlined in this review. Direct metabolic effects in additon to centrally controlled endocrine loops exert suppressive effects on bone formation and may also stimulate bone Resorption. Decreased bone formation in combination with increased bone resorption strongly increases fracture risk.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Bone ; Diabetes
ISSN (print) / ISBN
0947-7349
e-ISSN
1439-3646
Quellenangaben
Volume: 26,
Pages: 90-94
Publisher
Thieme
Publishing Place
Stuttgart
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Cancer (IDC)