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Hyde, D.* ; Miller, E.* ; Brooks, D.* ; Ntziachristos, V.

Differential equation-driven regularization for joint FMT-CT imaging.

In: (IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009. ISBI '09, 28 June-1 July 2009). 2009.
DOI
A primary motivation for multi-modal imaging is to improve reconstructions for low resolution functional modalities using high resolution structural information. Most such approaches assume that the anatomic and functional images share a common physical structure. For fluorescence molecular tomography (FMT), however, this may be only approximately valid. We thus present and analyze a regularization scheme that allows more flexible use of anatomic images. Using parallels between regularization and statistical modeling, we develop a stochastic PDE that shares information across structural boundaries. Simulations indicate that our approach is capable of obtaining more accurate reconstructions than methods treating each tissue independently.
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Publication type Article: Conference contribution
Corresponding Author
Keywords Differential equations, Fluorescence, Image reconstruction, Spatial resolution, Covariance matrix, Tomography, Inverse problems, Image resolution, In vivo, Probes
ISSN (print) / ISBN 1945-7928
Conference Title IEEE International Symposium on Biomedical Imaging: From Nano to Macro, 2009. ISBI '09
Conference Date 28 June-1 July 2009
Non-patent literature Publications
Institute(s) Institute of Biological and Medical Imaging (IBMI)