PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Estrada, H. ; Rebling, J. ; Razansky, D.

Prediction and near-field observation of skull-guided acoustic waves.

Phys. Med. Biol. 62, 4728-4740 (2017)
Postprint DOI PMC
Open Access Green
Ultrasound waves propagating in water or soft biological tissue are strongly reflected when encountering the skull, which limits the use of ultrasound-based techniques in transcranial imaging and therapeutic applications. Current knowledge on the acoustic properties of the cranial bone is restricted to far-field observations, leaving its near-field unexplored. We report on the existence of skull-guided acoustic waves, which was herein confirmed by near-field measurements of optoacoustically-induced responses in ex-vivo murine skulls immersed in water. Dispersion of the guided waves was found to reasonably agree with the prediction of a multilayered flat plate model. We observed a skull-guided wave propagation over a lateral distance of at least 3 mm, with a half-decay length in the direction perpendicular to the skull ranging from 35 to 300 μm at 6 and 0.5 MHz, respectively. Propagation losses are mostly attributed to the heterogenous acoustic properties of the skull.. It is generally anticipated that our findings may facilitate and broaden the application of ultrasound-mediated techniques in brain diagnostics and therapy.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
2.742
1.470
10
11
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Scientific Article
Keywords Guided Acoustic Waves ; Murine Skull ; Near Field ; Optoacoustic ; Photoacoustic ; Ultrasound; Murine Skull; Ultrasound; Bone; Transmission; Attenuation; Absorption; Microscopy; Solids; Speed; Sound
Language english
Publication Year 2017
HGF-reported in Year 2017
ISSN (print) / ISBN 0031-9155
e-ISSN 1361-6560
Journal Physics in Medicine and Biology
Quellenangaben Volume: 62, Issue: 12, Pages: 4728-4740 Article Number: , Supplement: ,
Publisher Institute of Physics Publishing (IOP)
Publishing Place Bristol
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s) 30205 - Bioengineering and Digital Health
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-505590-001
DOI 10.1088/1361-6560/aa63e3
WOS ID WOS:000401615200007
Scopus ID 85020411242
PubMed ID 28248639
Erfassungsdatum 2017-04-11
[➜Report correction]