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Wissmeyer, G. ; Shnaiderman, R. ; Soliman, D. ; Ntziachristos, V.

Optoacoustic microscopy based on pi-FBG ultrasound sensors.

Proc. SPIE 10064:1006423 (2017)
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Open Access Green
We present an optoacoustic (photoacoustic) microscopy (OAM) imaging system that uses a pi-shifted Fiber Bragg Grating (pi-FBG) as ultrasound (US) sensor. The sensor has an ultra-small footprint and hence allows for the detection of optoacoustic signals in close proximity to their origin. The interrogation of the pi-FBG is performed by a broadband pulsed laser, enabling a high sensitivity of the sensor as well as the elimination of ambient noise. We characterize the pi-FBG in terms of axial and lateral resolution as well as its bandwidth and find that its performance is comparable to US sensors that are based on the piezoelectric effect. We demonstrate the system’s capabilities by images taken from ex vivo zebrafish and mouse ear samples. The results presented herein highlight that pi-FBGs are a promising tool for the comprehensive label-free optoacoustic imaging of biomedical samples.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Optoacoustic microscopy; photoacoustic microscopy; interferometric detection of ultrasound; Fiber Bragg-Grating
Language english
Publication Year 2017
HGF-reported in Year 2017
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Conference Title Photons Plus Ultrasound: Imaging and Sensing 2017
Conference Date 28.01. – 02.02.2017
Conference Location San Francisco, California, United States
Journal Proceedings of SPIE
Quellenangaben Volume: 10064, Issue: , Pages: , Article Number: 1006423 Supplement: ,
Publisher SPIE
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s) 30205 - Bioengineering and Digital Health
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-505500-001
DOI 10.1117/12.2253066
Scopus ID 85019201748
Erfassungsdatum 2017-03-20
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