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Recent advances in treating Parkinson's disease.
F1000 Res. 6:260 (2017)
This article summarizes (1) the recent achievements to further improve symptomatic therapy of motor Parkinson's disease (PD) symptoms, (2) the still-few attempts to systematically search for symptomatic therapy of non-motor symptoms in PD, and (3) the advances in the development and clinical testing of compounds which promise to offer disease modification in already-manifest PD. However, prevention (that is, slowing or stopping PD in a prodromal stage) is still a dream and one reason for this is that we have no consensus on primary endpoints for clinical trials which reflect the progression in prodromal stages of PD, such as in rapid eye movement sleep behavior disorder (RBD) -a methodological challenge to be met in the future.
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Publication type
Article: Journal article
Document type
Review
Keywords
Parkinson's Disease ; Disease Modifying Treatment ; Motor Symptoms ; Non-motor Symptoms ; Prodromal Stage
e-ISSN
2046-1402
Journal
Faculty of 1000 Research
Quellenangaben
Volume: 6,
Article Number: 260
Publisher
BioMed Central
Publishing Place
London
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Neurogenomics (ING)