PuSH - Publication Server of Helmholtz Zentrum München: The feasibility of salivary sample collection in an international pediatric cohort: The the TEDDY study.

Navigation

Home

Deutsch

Research

Advanced Search

Browse by ...

... Journal

... Publication Type

... Research Data

... Publication Year

Publication overview

Support & Contact

Contact persons

Help

Data protection

TEDDY Study Group (Roth, R. ; Strauss, E.) ; Baxter, J.* ; Vehik, K.* ; Hopkins, D.* ; Killian, M.* ; Gesualdo, P.* ; Melin, J.* ; Simell, B.* ; Lernmark, A.* ; Johnson, S.B.*

The feasibility of salivary sample collection in an international pediatric cohort: The the TEDDY study.

Dev. Psychobiol. 59, 658-667 (2017)

Postprint

DOI

PMC

	Open Access Green

Abstract
Metrics
Extra information

Saliva offers a relatively noninvasive method for measuring analytes such as cortisol, holding particular promise for use in pediatric populations on a large scale if a rigorous collection protocol is feasible in diverse settings. The Environmental Determinants of Diabetes in the Young study protocol, conducted in centers in the United States, Sweden, Finland, and Germany, used salivary collection to assess cortisol level as a physiologic marker of stress. Saliva was collected using Sorbettes from subjects at 3.5, 4.5, and 5.5 years of age. Parents collected a morning sample, and staff collected pre- and post-blood draw samples. Feasibility was assessed based on protocol completion, adherence with instructions, factors affecting adherence, and sufficiency of saliva sample for cortisol determination. Collection of saliva samples in a diverse pediatric population is feasible. Establishing non-invasive and acceptable methods for collecting physiological parameters of stress will allow better exploration of determinants of health in this important population.

Altmetric

Additional Metrics?

[➜Log in]

Edit extra informations Login

Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords Adherence ; Methodological Feasibility ; Multi-center International ; Pediatric Cohort Study ; Salivary Collection ; Salivary Cortisol; Cortisol Awakening Response; Alpha-amylase; Children; Infants; Determinants; Associations; Withdrawal; Stress; Health; Tool

ISSN (print) / ISBN 0012-1630

e-ISSN 1098-2302

Journal Developmental psychobiology

Quellenangaben Volume: 59, Issue: 5, Pages: 658-667

Publisher Wiley

Publishing Place Hoboken, NJ

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Diabetes Research Type 1 (IDF)