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Hybrid-array-based optoacoustic and ultrasound (OPUS) imaging of biological tissues.
Appl. Phys. Lett. 110:203703 (2017)
Publ. Version/Full Text
DOI
Hybrid optoacoustic and pulse-echo ultrasound imaging is an attractive multi-modal combination owing to the highly complementary contrast of the two techniques. Efficient hybridization is often hampered by significant dissimilarities between their optimal data acquisition and image formation strategies. Herein, we introduce an approach for combined optoacoustic and ultrasound imaging based on a plano-concave detector array design with a non-uniform pitch distribution. The hybrid design optimized for both modalities allows for maintaining an extended field of view for efficient ultrasound navigation while simultaneously providing broad tomographic coverage for optimal optoacoustic imaging performance. Imaging sessions performed in tissue-mimicking phantoms and healthy volunteers demonstrate that the suggested approach renders an enhanced imaging performance as compared with the previously reported hybrid optoacoustic and ultrasound imaging approaches. Thus, it can greatly facilitate clinical translation of the optoacoustic imaging technology by means of its efficient combination with ultrasonography, a well-established clinical imaging modality.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Photoacoustic Tomography; In-vivo; System; Enhancement
ISSN (print) / ISBN
0003-6951
e-ISSN
1077-3118
Journal
Applied Physics Letters
Quellenangaben
Volume: 110,
Issue: 20,
Article Number: 203703
Publisher
American Institute of Physics (AIP)
Publishing Place
Melville
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)