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Novel approaches for targeting thymidylate synthase to overcome the resistance and toxicity of anticancer drugs.
J. Med. Chem. 53, 6539-6549 (2010)
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
histone deacetylase inhibitor; enhances 5-fluorouracil cytotoxicity; dihydrofolate-reductase inhibitors; messenger-rna translation; colon-cancer cells; gene-expression; in-vitro; colorectal-cancer; biological evaluation; antitumor-activity
Language
english
Publication Year
2010
HGF-reported in Year
2010
ISSN (print) / ISBN
0022-2623
e-ISSN
1520-4804
Journal
Journal of Medicinal Chemistry
Quellenangaben
Volume: 53,
Issue: 18,
Pages: 6539-6549
Publisher
American Chemical Society (ACS)
Reviewing status
Peer reviewed
Institute(s)
Institute of Structural Biology (STB)
POF-Topic(s)
30203 - Molecular Targets and Therapies
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-503000-001
PubMed ID
20527892
Scopus ID
77956759532
Erfassungsdatum
2010-12-31