PuSH - Publication Server of Helmholtz Zentrum München

Export: TXT Text RIS Endnote (RIS) BIB BibTeX
Rychlik, M.* ; Kanawati, B. ; Schmitt-Kopplin, P.

Foodomics as a promising tool to investigate the mycobolome.

Trends Analyt. Chem. 96, 22-30 (2017)
Postprint DOI
Open Access Green
The huge variety of mycotoxins requires mass spectrometric approaches as they are applied to metabolomics in its targeted and non-targeted analytical forms. For quantitation of mycotoxins in targeted metabolomics, liquid chromatography coupled to triple quadrupole, Orbitrap™ or time-of-flight mass spectrometers provide accurate results. For identification in non-targeted metabolomics, combinations of UPLC and high resolution mass spectrometry (HRMS) are desirable, but mass resolution is compromised by the mass analyzer's scan rates, required for UPLC. In this review, the application of Orbitrap™, time-of-flight and FT-ICR-MS techniques to mycotoxin research is covered and compared to each other. A superior advantage of all HRMS instruments is that they allow a retrospective data treatment thus preserving the information for later reprocessing. Up to date, ultra high resolving FT-ICR-MS is the only method to unequivocally assign elementary sum formulae but cannot be coupled to UPLC without losing resolution power.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Scopus
Cited By
Altmetric
8.442
2.199
13
23
Tags
Annotations
Special Publikation
Hide on homepage

Edit extra information
Edit own tags
Private
Edit own annotation
Private
Hide on publication lists
on hompage
Mark as special
publikation
Publication type Article: Journal article
Document type Scientific Article
Keywords Ft-icr-ms ; High Resolution Mass Spectrometry ; Metabolomics ; Modified Mycotoxins ; Mycobolome ; Orbitrap ; Time Of Flight; Isotope Dilution Assays; Orbitrap Mass-spectrometry; Liquid-chromatography; Future Perspectives; Aspergillus-flavus; Fungal Metabolites; Mycotoxin Analysis; Alternaria Toxins; Fusarium Toxins; Food Matrices
Language english
Publication Year 2017
HGF-reported in Year 2017
ISSN (print) / ISBN 0165-9936
e-ISSN 1873-3689
Journal TrAC Trends in Analytical Chemistry
Quellenangaben Volume: 96, Issue: , Pages: 22-30 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Oxford
Reviewing status Peer reviewed
Institute(s) Research Unit BioGeoChemistry and Analytics (BGC)
POF-Topic(s) 30202 - Environmental Health
Research field(s) Environmental Sciences
PSP Element(s) G-504800-001
DOI 10.1016/j.trac.2017.05.006
WOS ID WOS:000415910300004
Scopus ID 85020644153
Erfassungsdatum 2017-07-20
[➜Report correction]