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Ravichandran, M.* ; Grandl, G. ; Ristow, M.*

Dietary carbohydrates impair healthspan and promote mortality.

Cell Metab. 26, 585-587 (2017)
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The prospective cohort study, named PURE, found that in >135,000 participants from 18 countries, nutritive carbohydrates increase human mortality, whereas dietary fat reduces it, requesting a fundamental change of current nutritional guidelines. Experimental evidence from animal models provides synergizing mechanistic concepts as well as pharmacological options to mimic low-carb or ketogenic diets.
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Publication type Article: Journal article
Document type Review
Keywords Life-span; Longevity; Mice; Respiration
Language english
Publication Year 2017
HGF-reported in Year 2017
ISSN (print) / ISBN 1550-4131
e-ISSN 1932-7420
Journal Cell Metabolism
Quellenangaben Volume: 26, Issue: 4, Pages: 585-587 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Cambridge
Reviewing status Peer reviewed
POF-Topic(s) 30201 - Metabolic Health
Research field(s) Helmholtz Diabetes Center
PSP Element(s) G-502200-007
PubMed ID 28978421
Erfassungsdatum 2017-10-10