Home
Deutsch
Advanced Search
Browse by ...
Publication overview
Contact persons
Help
DOI
 |
|
Open Access Green as soon as Postprint is submitted to ZB.
Intramyocellular lipids and their dynamics assessed by 1H magnetic resonance spectroscopy.
Clin. Physiol. & Func. Im. 37, 558-566 (2017)
This report provides an overview on the present knowledge on intramyocellular lipids (IMCL) and their dynamics in the course of interventions with physical activity of variable type and intensity in different population groups, as accessible by examinations using non-invasive volume-selective H-1 magnetic resonance spectroscopy (H-1 MRS). IMCL serve as energy source in skeletal muscle for fat oxidation in the mitochondria and became intensively studied after discovery of their relation with insulin sensitivity. While baseline levels of IMCL concentration have been shown to be mainly dependent on the metabolic status (insulin sensitivity), on the level of training and on fibre composition in the muscles, studies applying different physical activity protocols revealed the dynamic of their depletion and replenishment. From the findings in human studies, it can be concluded that IMCL levels are potentially useful markers for monitoring metabolic adaptation of skeletal muscle to sportive activities and training.
Altmetric
Additional Metrics?
Edit extra informations
Login
Publication type
Article: Journal article
Document type
Review
Keywords
H-1-mrs ; Intramyocellular Lipids ; Metabolic Adaptation ; Physical Activity Intervention ; Skeletal Muscle; Human Skeletal-muscle; Insulin-resistance; Mr Spectroscopy; Proton Mr; Mitochondrial Dysfunction; Fatty-acids; 1h Mrsi; Exercise; Humans; Acetylcarnitine
ISSN (print) / ISBN
1475-0961
e-ISSN
1475-097X
Quellenangaben
Volume: 37,
Issue: 6,
Pages: 558-566
Publisher
Blackwell
Publishing Place
Oxford
Non-patent literature
Publications
Reviewing status
Peer reviewed