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Optical and optoacoustic imaging in the diffusive regime
In: Handbook of Photonics for Biomedical Engineering. 2017. 221-246
Optical imaging is capable of providing valuable molecular contrast, cell tracking, genetic reporters, and a wide range of biomarkers that reveal the biological processes underlying a disease. For centuries, optical imaging has primarily been confined to superficial tissue layers, due to the high scattering of photons in tissue. Optical tomographic methods based on accurate models of diffusive deep-tissue light propagation have allowed fluorescence and endogenous contrast to be visualized and volumetrically quantified at depths of centimeters. Emerging optoacoustic methods allow optical absorption contrast to be pinpointed at high spatial resolutions by means of ultrasound waves, breaking through the resolution limitations imposed by diffusive light. This chapter introduces the principles of optical and optoacoustic methods for imaging biomedically relevant contrast in the diffusive regime.
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Publication type
Article: Edited volume or book chapter
Keywords
Optical Imaging ; Optoacoustic Imaging
Language
Publication Year
2017
HGF-reported in Year
2017
ISSN (print) / ISBN
9789400750524
Book Volume Title
Handbook of Photonics for Biomedical Engineering
Quellenangaben
Pages: 221-246
Institute(s)
Institute of Biological and Medical Imaging (IBMI)
POF-Topic(s)
30205 - Bioengineering and Digital Health
Research field(s)
Enabling and Novel Technologies
PSP Element(s)
G-505500-001
Scopus ID
85034394151
Erfassungsdatum
2017-12-11