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Immune responses - Transcriptional and post-transcriptional networks pass the baton.
Trends Biochem. Sci. 43, 1-4 (2018)
Diverse gene regulatory mechanisms impact on immune homeostasis, and a new model now emerges as fundamental in light of recent genome-wide studies. In this picture, transcriptional networks drive functional changes during immune activation, whereas autoregulatory feedback loops of post-transcriptional programs ensure the original cell lineage identity and subsequent immune resolution.
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Publication type
Article: Journal article
Document type
Review
Keywords
Dynamic Rna Sequencing ; Immune Response ; Regulators Of Immune Function ; Rna-binding Proteins ; Transcription ; Translational Control; Rna-binding Proteins
ISSN (print) / ISBN
0376-5067
e-ISSN
0968-0004
Quellenangaben
Volume: 43,
Issue: 1,
Pages: 1-4
Publisher
Elsevier
Publishing Place
Cambridge
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Diabetes and Obesity (IDO)