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Immune responses - Transcriptional and post-transcriptional networks pass the baton.

Trends Biochem. Sci. 43, 1-4 (2018)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Diverse gene regulatory mechanisms impact on immune homeostasis, and a new model now emerges as fundamental in light of recent genome-wide studies. In this picture, transcriptional networks drive functional changes during immune activation, whereas autoregulatory feedback loops of post-transcriptional programs ensure the original cell lineage identity and subsequent immune resolution.
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Publication type Article: Journal article
Document type Review
Keywords Dynamic Rna Sequencing ; Immune Response ; Regulators Of Immune Function ; Rna-binding Proteins ; Transcription ; Translational Control; Rna-binding Proteins
Language english
Publication Year 2018
Prepublished in Year 2017
HGF-reported in Year 2017
ISSN (print) / ISBN 0376-5067
e-ISSN 0968-0004
Quellenangaben Volume: 43, Issue: 1, Pages: 1-4 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Cambridge
Reviewing status Peer reviewed
POF-Topic(s) 90000 - German Center for Diabetes Research
Research field(s) Helmholtz Diabetes Center
PSP Element(s) G-501900-226
Scopus ID 85035115674
PubMed ID 29239765
Erfassungsdatum 2017-12-12