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Knieling, F.* ; Gonzales-Menezes, J.* ; Claussen, J.* ; Schwarz, M.A.* ; Neufert, C.* ; Fahlbusch, F.B.* ; Rath, T.* ; Thoma, O.M.* ; Kramer, V.* ; Menchicchi, B.* ; Kersten, C.* ; Scheibe, K.* ; Schürmann, S.* ; Carlé, B.* ; Rascher, W.* ; Neurath, M.F.* ; Ntziachristos, V. ; Waldner, M.J.*

Raster-scanning optoacoustic mesoscopy for gastrointestinal imaging at high resolution.

Gastroenterology 154, 807-809.e3 (2018)
Postprint DOI PMC
Open Access Green
In vivo optical imaging modalities are mostly limited to cell cultures, superficial tissues, and intravital imaging since they lack either resolution or penetration depth.1 In contrast, optoacoustic (OA) imaging—combining features of optical and ultrasound imaging—has been used to visualize hemoglobin in depths of approximately 3 cm in patients with Crohn’s disease.2,3 Realizing an even higher resolution, raster-scanning OA mesoscopy (RSOM) provides intrinsic optical tissue contrast down to 10-20 μm resolution at still high penetration depths of several millimeters.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Inflammatory-bowel-disease; Tomography; Microscopy
ISSN (print) / ISBN 0016-5085
e-ISSN 1528-0012
Journal Gastroenterology
Quellenangaben Volume: 154, Issue: 4, Pages: 807-809.e3 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Philadelphia
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)