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Minimal analytical characterization of engineered nanomaterials needed for hazard assessment in biological matrices.
Nanotox. 5, 1-11 (2011)
This paper presents the outcomes from a workshop of the European Network on the Health and Environmental Impact of Nanomaterials (NanoImpactNet). During the workshop, 45 experts in the field of safety assessment of engineered nanomaterials addressed the need to systematically study sets of engineered nanomaterials with specific metrics to generate a data set which would allow the establishment of dose-response relations. The group concluded that international cooperation and worldwide standardization of terminology, reference materials and protocols are needed to make progress in establishing lists of essential metrics. High quality data necessitates the development of harmonized study approaches and adequate reporting of data. Priority metrics can only be based on well-characterized dose-response relations derived from the systematic study of the bio-kinetics and bio-interactions of nanomaterials at both organism and (sub)-cellular levels. In addition, increased effort is needed to develop and validate analytical methods to determine these metrics in a complex matrix. Read More: http://informahealthcare.com/doi/abs/10.3109/17435391003775266
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Nanomaterials; Characterization; Metrics; Nanotoxicology; Hazard assessment
ISSN (print) / ISBN
1743-5390
e-ISSN
1743-5404
Journal
Nanotoxicology
Quellenangaben
Volume: 5,
Issue: 1,
Pages: 1-11
Publisher
Informa Healthcare
Publishing Place
London
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Lung Biology (LHI)