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Hofweber, M.* ; Hutten, S.* ; Bourgeois, B.* ; Spreitzer, E.* ; Niedner-Boblenz, A. ; Schifferer, M.* ; Ruepp, M.D.* ; Simons, M.* ; Niessing, D. ; Madl, T.* ; Dormann, D.*

Phase separation of FUS is suppressed by its nuclear import receptor and arginine methylation.

Cell 173, 706-719.e13 (2018)
Publ. Version/Full Text Research data DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
Purpose of Review Advances in technology have expanded telemedicine opportunities covering medical practice, research, and education. This is of particular importance in movement disorders (MDs), where the combination of disease progression, mobility limitations, and the sparse distribution of MD specialists increase the difficulty to access. In this review, we discuss the prospects, challenges, and strategies for telemedicine in MDs.Recent Findings Telemedicine for MDs has been mainly evaluated in Parkinson's disease (PD) and compared to in-office care is cost-effective with similar clinical care, despite the barriers to engagement. However, particular groups including pediatric patients, rare MDs, and the use of telemedicine in underserved areas need further research.Summary Interdisciplinary telemedicine and tele-education for MDs are feasible, provide similar care, and reduce travel costs and travel time compared to in-person visits. These benefits have been mainly demonstrated for PD but serve as a model for further validation in other movement disorders.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Als ; Ftd ; Karyopherin-β2 (kapβ2) ; Transportin (tnpo1) ; Arginine Methylation ; Fused In Sarcoma (fus) ; Neurodegeneration ; Nuclear Import ; Phase Separation ; Stress Granules; Randomized Controlled-trial; Chronic Tic Disorders; Parkinsons-disease; Health-care; Tourette-syndrome; Behavior-therapy; Neurological Disorders; Huntington Disease; Batten-disease; Virtual Visits
Language
Publication Year 2018
HGF-reported in Year 2018
ISSN (print) / ISBN 0092-8674
e-ISSN 1097-4172
Journal Cell
Quellenangaben Volume: 173, Issue: 3, Pages: 706-719.e13 Article Number: , Supplement: ,
Publisher Cell Press
Publishing Place Cambridge, Mass.
Reviewing status Peer reviewed
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-503091-001
Scopus ID 85045120263
PubMed ID 29677514
Erfassungsdatum 2018-06-22