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Hofweber, M.* ; Hutten, S.* ; Bourgeois, B.* ; Spreitzer, E.* ; Niedner-Boblenz, A. ; Schifferer, M.* ; Ruepp, M.D.* ; Simons, M.* ; Niessing, D. ; Madl, T.* ; Dormann, D.*

Phase separation of FUS is suppressed by its nuclear import receptor and arginine methylation.

Cell 173, 706-719.e13 (2018)

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Purpose of Review Advances in technology have expanded telemedicine opportunities covering medical practice, research, and education. This is of particular importance in movement disorders (MDs), where the combination of disease progression, mobility limitations, and the sparse distribution of MD specialists increase the difficulty to access. In this review, we discuss the prospects, challenges, and strategies for telemedicine in MDs.Recent Findings Telemedicine for MDs has been mainly evaluated in Parkinson's disease (PD) and compared to in-office care is cost-effective with similar clinical care, despite the barriers to engagement. However, particular groups including pediatric patients, rare MDs, and the use of telemedicine in underserved areas need further research.Summary Interdisciplinary telemedicine and tele-education for MDs are feasible, provide similar care, and reduce travel costs and travel time compared to in-person visits. These benefits have been mainly demonstrated for PD but serve as a model for further validation in other movement disorders.

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Publication type Article: Journal article

Document type Scientific Article

Corresponding Author

Keywords Als ; Ftd ; Karyopherin-β2 (kapβ2) ; Transportin (tnpo1) ; Arginine Methylation ; Fused In Sarcoma (fus) ; Neurodegeneration ; Nuclear Import ; Phase Separation ; Stress Granules; Randomized Controlled-trial; Chronic Tic Disorders; Parkinsons-disease; Health-care; Tourette-syndrome; Behavior-therapy; Neurological Disorders; Huntington Disease; Batten-disease; Virtual Visits

ISSN (print) / ISBN 0092-8674

e-ISSN 1097-4172

Journal Cell

Quellenangaben Volume: 173, Issue: 3, Pages: 706-719.e13

Publisher Cell Press

Publishing Place Cambridge, Mass.

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute of Structural Biology (STB)