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Mewes, H.-W. ; Frishman, D.* ; Mayer, K.F.X. ; Münsterkötter, M. ; Noubibou, O. ; Pagel, P. ; Rattei, T.* ; Oesterheld, M. ; Ruepp, A. ; Stuempflen, V.

MIPS: Analysis and annotation of proteins from whole genomes in 2005.

Nucleic Acids Res. 34, D169-D172 (2006)
Publ. Version/Full Text Volltext DOI PMC
Open Access Gold
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The Munich Information Center for Protein Sequences (MIPS at the GSF), Neuherberg, Germany, provides resources related to genome information. Manually curated databases for several reference organisms are maintained. Several of these databases are described elsewhere in this and other recent NAR database issues. In a complementary effort, a comprehensive set of >400 genomes automatically annotated with the PEDANT system are maintained. The main goal of our current work on creating and maintaining genome databases is to extend gene centered information to information on interactions within a generic comprehensive framework. We have concentrated our efforts along three lines (i) the development of suitable comprehensive data structures and database technology, communication and query tools to include a wide range of different types of information enabling the representation of complex information such as functional modules or networks Genome Research Environment System, (ii) the development of databases covering computable information such as the basic evolutionary relations among all genes, namely SIMAP, the sequence similarity matrix and the CABiNet network analysis framework and (iii) the compilation and manual annotation of information related to interactions such as protein-protein interactions or other types of relations (e.g. MPCDB, MPPI, CYGD). All databases described and the detailed descriptions of our projects can be accessed through the MIPS WWW server (http://mips.gsf.de).
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords DNA-SEQUENCE; DATABASE; NETWORKS; TOOL
ISSN (print) / ISBN 0305-1048
e-ISSN 1362-4962
Journal Nucleic Acids Research
Quellenangaben Volume: 34, Issue: SI, Pages: D169-D172 Article Number: , Supplement: ,
Publisher Oxford University Press
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Bioinformatics and Systems Biology (IBIS)