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Pogue, B.W.* ; Zhu, T.C.* ; Ntziachristos, V. ; Paulsen, K.D.* ; Wilson, B.C.* ; Pfefer, J.* ; Nordstrom, R.J.* ; Litorja, M.* ; Wabnitz, H.* ; Chen, Y.* ; Gioux, S.* ; Tromberg, B.J.* ; Yodh, A.G.*

Fluorescence-guided surgery and intervention - An AAPM emerging technology blue paper.

Med. Phys. 45, 2681-2688 (2018)
Postprint DOI PMC
Open Access Green
Fluorescence-guided surgery (FGS) and other interventions are rapidly evolving as a class of technologically driven interventional approaches in which many surgical specialties visualize fluorescent molecular tracers or biomarkers through associated cameras or oculars to guide clinical decisions on pathological lesion detection and excision/ablation. The technology has been commercialized for some specific applications, but also presents technical challenges unique to optical imaging that could confound the utility of some interventional procedures where real-time decisions must be made. Accordingly, the AAPM has initiated the publication of this Blue Paper of The Emerging Technology Working Group (TETAWG) and the creation of a Task Group from the Therapy Physics Committee within the Treatment Delivery Subcommittee. In describing the relevant issues, this document outlines the key parameters, stakeholders, impacts, and outcomes of clinical FGS technology and its applications. The presentation is not intended to be conclusive, but rather to inform the field of medical physics and stimulate the discussions needed in the field with respect to a seemingly low-risk imaging technology that has high potential for significant therapeutic impact. This AAPM Task Group is working toward consensus around guidelines and standards for advancing the field safely and effectively.
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Publication type Article: Journal article
Document type Other: Opinion
Corresponding Author
Keywords Imaging ; Imaging System ; Intervention ; Molecular ; Molecular Probe ; Resection; Indocyanine Green Icg; Protoporphyrin-ix Fluorescence; Detecting Sentinel Nodes; 5-aminolevulinic Acid; In-vivo; Photodynamic Therapy; Cancer; Tumors; Visualization; Angiography
ISSN (print) / ISBN 0094-2405
e-ISSN 1522-8541
Journal Medical Physics
Quellenangaben Volume: 45, Issue: 6, Pages: 2681-2688 Article Number: , Supplement: ,
Publisher American Institute of Physics (AIP)
Publishing Place 111 River St, Hoboken 07030-5774, Nj Usa
Non-patent literature Publications
Reviewing status Peer reviewed
Institute(s) Institute of Biological and Medical Imaging (IBMI)