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Dosimetric characterization of a single crystal diamond detector in X-ray beams for preclinical research.
Dosimetrische Charakterisierung eines Einkristall-Diamant-Detektors in Röntgenstrahlen zur präklinischen Forschung.
Z. Med. Phys. 28, 303-309 (2018)
The aim of this study was to investigate a single crystal diamond detector, the microDiamond detector from PTW (PTW-Freiburg, Freiburg, Germany), concerning the particular requirements in the set-up and energy range used in small animal radiotherapy (RT) research (around 220 kV). We tested it to find out the minimal required pre-irradiation dose, the dose linearity, dose rate dependency and the angular response as well as usability in the small animal radiation research platform, SARRP (Xstrahl Ltd., Camberley, UK).For a stable signal in the range of energies used in the study, we found a required pre-irradiation dose of 10 Gy. The dose linearity and dose rate dependence measurements showed a very good performance of the microDiamond detector. Regarding the effect of angular dependency, the variation of the response signal is less than 0.5% within the first 15 degrees of the polar angle. In the azimuthal angle, however, there are differences in detector response up to 20%, depending on the range of energies used in the study. In addition, we compared the detector to a radiosensitive film for a profile measurement of a 5 x 5 mm(2) irradiation field. Both methods showed a good accordance with the field size, however, the film has a steeper dose gradient in the penumbra region but also a higher noise than the microDiamond detector.We demonstrated that the microDiamond detector is a useful measurement tool for small animal RT research due to its small size. Nevertheless, it seems to be very important to verify the response of the detector in the given set-up and energy range.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Microdiamond Detector ; X-ray ; Dosimetry ; Small Animal Irradiation; Radiation Research Platform; Med. Phys. 43; Active Area; Photon; Electron
ISSN (print) / ISBN
0939-3889
e-ISSN
1876-4436
Quellenangaben
Volume: 28,
Issue: 4,
Pages: 303-309
Publisher
Elsevier
Publishing Place
Po Box 211, 1000 Ae Amsterdam, Netherlands
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Radiation Medicine (IRM)