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Open Access Green as soon as Postprint is submitted to ZB.
Monitoring of tissue heating with medium intensity focused ultrasound via four dimensional optoacoustic tomography.
Proc. SPIE 10494:104945J (2018)
Downloading of the abstract is permitted for personal use only. Medium intensity focused ultrasound (MIFU) holds promise in important clinical applications. Generally, the aim in MIFU is to stimulate physiological mechanisms that reinforce healing responses, avoiding reaching temperatures that can cause permanent tissue damage. The outcome of interventions is then strongly affected by the temperature distribution in the treated region, and accurate monitoring represents a significant clinical need. In this work, we showcase the capacities of 4D optoacoustic imaging to monitor tissue heating during MIFU. The proposed method allows localizing the ultrasound focus, estimating the peak temperature and measuring the size of the heat-affected volume. Calibration experiments in a tissue-mimicking phantom demonstrate that the optoacoustically-estimated temperature accurately matches thermocouple readings. The good performance of the suggested approach in real tissues is further showcased in experiments with bovine muscle samples.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Photoacoustic Imaging ; Temperature ; Thermal Imaging ; Ultrasound Diagnostics
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
Journal
Proceedings of SPIE
Quellenangaben
Volume: 10494,
Article Number: 104945J
Publisher
SPIE
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)