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Lu, T.* ; Wang, Y.* ; Gao, F.* ; Zhao, H.* ; Ntziachristos, V. ; Li, J.*

Spatial-impulse-response-dependent back-projection using the non-stationary convolution in optoacoustic mesoscopy.

Proc. SPIE 10494:104943R (2018)
DOI
Open Access Green as soon as Postprint is submitted to ZB.
Photoacoustic mesoscopy (PAMe), offering high-resolution (sub-100-μm) and high optical contrast imaging at the depth of 1-10 mm, generally obtains massive collection data using a high-frequency focused ultrasonic transducer. The spatial impulse response (SIR) of this focused transducer causes the distortion of measured signals in both duration and amplitude. Thus, the reconstruction method considering the SIR needs to be investigated in the computation-economic way for PAMe. Here, we present a modified back-projection algorithm, by introducing a SIR-dependent calibration process using a non-satationary convolution method. The proposed method is performed on numerical simulations and phantom experiments of microspheres with diameter of both 50 μm and 100 μm, and the improvement of image fidelity of this method is proved to be evident by methodology parameters. The results demonstrate that, the images reconstructed when the SIR of transducer is accounted for have higher contrast-to-noise ratio and more reasonable spatial resolution, compared to the common back-projection algorithm.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Non-stationary Convolution ; Photoacoustic Mesoscopy ; Reconstruction Algorithms ; Spatial Impulse Response
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Quellenangaben Volume: 10494, Issue: , Pages: , Article Number: 104943R Supplement: ,
Publisher SPIE
Non-patent literature Publications
Reviewing status Peer reviewed