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Schwarz, P.E. ; Timpel, P.* ; Harst, L.* ; Greaves, C.J.* ; Ali, M.K.* ; Lambert, J.C.* ; Weber, M.B.* ; Almedawar, M.M.* ; Morawietz, H.*

Blood sugar regulation for cardiovascular health promotion and disease prevention JACC health promotion series.

J. Am. Coll. Cardiol. 72, 1829-1844 (2018)

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The primary objective of this study was to analyze the most up-to-date evidence regarding whether and how blood sugar regulation influences cardiovascular health promotion and disease prevention by carrying out an umbrella review. Three separate, systematic literature searches identified 2,343 papers in total. Overall, 44 studies were included for data extraction and analysis. The included systematic reviews and meta-analyses published between January 1, 2016, and December 31, 2017, were of good to very good quality (median Overview Quality Assessment Questionnaire score = 17). Identified evidence suggests that cardiovascular disease (CVD) prevention services should consider regulation of blood glucose as a key target for intervention. Furthermore, the recommendations for effective intervention and service development/training described here for prevention of CVD should be adopted into evidence-based practice guidelines. Multidisciplinary teams should be formed to deliver multicomponent interventions in community-based settings. There may be substantial opportunities for integrating CVD and diabetes prevention services.

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Publication type Article: Journal article

Document type Review

Corresponding Author

Keywords Blood Glucose ; Diabetes Mellitus ; Diet ; Exercise ; Health Behavior ; Umbrella Review ; Weight Loss; Randomized Controlled-trials; Life-style Interventions; Type-2 Diabetes-mellitus; Percutaneous Coronary Intervention; Cotransporter 2 Inhibition; Self-management Education; Myocardial-infarction; Glucose Control; Behavior-change; Heart-failure

ISSN (print) / ISBN 0735-1097

e-ISSN 1558-3597

Journal Journal of the American College of Cardiology

Quellenangaben Volume: 72, Issue: 15, Pages: 1829-1844

Publisher Elsevier

Publishing Place New York, NY

Non-patent literature Publications

Reviewing status Peer reviewed

Institute(s) Institute for Pancreatic Beta Cell Research (IPI)