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Neuroplasticity in the acoustic startle reflex in larval zebrafish.
Curr. Opin. Neurobiol. 54, 134-139 (2019)
Learning is essential for animal survival under changing environments. Even in its simplest form, learning involves interactions between a handful of neuronal circuits, hundreds of neurons and many thousand synapses. In this review I will focus on habituation a form of non-associative learning during which organisms decrease their response to repetitions of identical sensory stimuli. I will discuss how recent studies of the acoustic startle reflex mediated by the Mauthner cell in the zebrafish larva are helping to understand the neuroplastic processes that underlie habituation. In addition to being a fascinating biological process, habituation is clinically relevant because it is affected in various neuropsychiatric disorders in humans, including autism, schizophrenia, Fragile-X and Tourette's syndromes.
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Publication type
Article: Journal article
Document type
Review
Keywords
Locomotor Repertoire; Habituation; Behavior; Circuit; System; Model; Activation; Mechanisms; Plasticity; Neurons
ISSN (print) / ISBN
0959-4388
e-ISSN
1873-6882
Journal
Current Opinion in Neurobiology
Quellenangaben
Volume: 54,
Pages: 134-139
Publisher
Elsevier
Publishing Place
84 Theobalds Rd, London Wc1x 8rr, England
Non-patent literature
Publications
Reviewing status
Peer reviewed