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Non-invasive imaging in dermatology and the unique potential of raster-scan optoacoustic mesoscopy.
J. Eur. Acad. Dermatol. Venereol. 33, 1051-1061 (2019)
Publ. Version/Full Text
Postprint
DOI
PMC
In recent years, several non-invasive imaging methods have been introduced to facilitate diagnostics and therapy monitoring in dermatology. The microscopic imaging methods are restricted in their penetration depth, while the mesoscopic methods probe deeper but provide only morphological, not functional, information. 'Raster-scan optoacoustic mesoscopy' (RSOM), an emerging new imaging technique, combines deep penetration with contrast based on light absorption, which provides morphological, molecular and functional information. Here, we compare the capabilities and limitations of currently available dermatological imaging methods and highlight the principles and unique abilities of RSOM. We illustrate the clinical potential of RSOM, in particular for non-invasive diagnosis and monitoring of inflammatory and oncological skin diseases.
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Publication type
Article: Journal article
Document type
Review
Keywords
Imaging Method ; Microvasculature ; Non-invasive Diagnosis ; Photoacoustic ; Skin Imaging; Optical Coherence Tomography; Reflectance Confocal Microscopy; Multiphoton Laser Tomography; High-frequency Sonography; In-vivo; Preoperative Assessment; Human Skin; Clinical-application; Tumor Thickness; High-resolution
ISSN (print) / ISBN
0926-9959
e-ISSN
1468-3083
Quellenangaben
Volume: 33,
Issue: 6,
Pages: 1051-1061
Publisher
Wiley
Publishing Place
111 River St, Hoboken 07030-5774, Nj Usa
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)