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Mahmutovic, L.* ; Akcesme, B.* ; Durakovic, C.* ; Akcesme, F.B.* ; Maric, A.* ; Adilovic, M.* ; Hamad, N.* ; Wjst, M. ; Feeney, O.* ; Semiz, S.*

Perceptions of students in health and molecular life sciences regarding pharmacogenomics and personalized medicine.

Hum. Genomics 12:50 (2018)
Publ. Version/Full Text DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
BackgroundIncreasing evidence is demonstrating that a patient's unique genetic profile can be used to detect the disease's onset, prevent its progression, and optimize its treatment. This led to the increased global efforts to implement personalized medicine (PM) and pharmacogenomics (PG) in clinical practice. Here we investigated the perceptions of students from different universities in Bosnia and Herzegovina (BH) towards PG/PM as well as related ethical, legal, and social implications (ELSI). This descriptive, cross-sectional study is based on the survey of 559 students from the Faculties of Medicine, Pharmacy, Health Studies, Genetics, and Bioengineering and other study programs.ResultsOur results showed that 50% of students heard about personal genome testing companies and 69% consider having a genetic test done. A majority of students (57%) agreed that PM represents a promising healthcare model, and 40% of students agreed that their study program is well designed for understanding PG/PM. This latter opinion seems to be particularly influenced by the field of study (7.23, CI 1.99-26.2, p=0.003). Students with this opinion are also more willing to continue their postgraduate education in the PM (OR=4.68, CI 2.59-8.47, p<0.001). Furthermore, 45% of students are aware of different ethical aspects of genetic testing, with most of them (46%) being concerned about the patient's privacy.ConclusionsOur results indicate a positive attitude of biomedical students in Bosnia and Herzegovina towards genetic testing and personalized medicine. Importantly, our results emphasize the key importance of pharmacogenomic education for more efficient translation of precision medicine into clinical practice.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Precision Medicine ; Pharmacogenomics ; Education ; Ethical ; Legal ; And Social Issues ; Survey; Ethical-issues; Care; Pharmacists; Education; Genetics; Future; Legal; Views; Us; Implementation
ISSN (print) / ISBN 1473-9542
e-ISSN 1479-7364
Journal Human genomics
Quellenangaben Volume: 12, Issue: 1, Pages: , Article Number: 50 Supplement: ,
Publisher Stewart
Publishing Place London
Non-patent literature Publications
Reviewing status Peer reviewed