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Open Access Green as soon as Postprint is submitted to ZB.
Approaching MALDI molecular imaging for clinical proteomic research: Current state and fields of application.
Expert Rev. Proteomics 7, 927-941 (2010)
MALDI imaging mass spectrometry ('MALDI imaging') is an increasingly recognized technique for biomarker research. After years of method development in the scientific community, the technique is now increasingly applied in clinical research. In this article, we discuss the use of MALDI imaging in clinical proteomics and put it in context with classical proteomics techniques. We also highlight a number of upcoming challenges for personalized medicine, development of targeted therapies and diagnostic molecular pathology where MALDI imaging could help.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
biomarker discovery; clinical proteomics; MALDI imaging; MALDI imaging mass spectrometry; molecular pathology; personalized medicine; tissue analysis
ISSN (print) / ISBN
1478-9450
e-ISSN
1744-8387
Journal
Expert Review of Proteomics
Quellenangaben
Volume: 7,
Issue: 6,
Pages: 927-941
Publisher
Expert Reviews
Non-patent literature
Publications
Reviewing status
Peer reviewed