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    Micelle-encapsulated quantum dot-porphyrin assemblies as in vivo two-photon oxygen sensors.
        
        J. Am. Chem. Soc. 137, 9832-9842 (2015)
    
    
    
	    Micelles have been employed to encapsulate the supramolecular assembly of quantum dots with palladium(II) porphyrins for the quantification of O2 levels in aqueous media and in vivo. Förster resonance energy transfer from the quantum dot (QD) to the palladium porphyrin provides a means for signal transduction under both one- and two-photon excitation. The palladium porphyrins are sensitive to O2 concentrations in the range of 0-160 Torr. The micelle-encapsulated QD-porphyrin assemblies have been employed for in vivo multiphoton imaging and lifetime-based oxygen measurements in mice with chronic dorsal skinfold chambers or cranial windows. Our results establish the utility of the QD-micelle approach for in vivo biological sensing applications.
	
	
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        Publication type
        Article: Journal article
    
 
    
        Document type
        Scientific Article
    
 
     
    
     
     
    
    
        Language
        english
    
 
    
        Publication Year
        2015
    
 
     
    
        HGF-reported in Year
        2015
    
 
    
    
        ISSN (print) / ISBN
        0002-7863
    
 
    
        e-ISSN
        1520-5126
    
 
    
     
     
	     
	 
	 
     
	
    
        Quellenangaben
        
	    Volume: 137,  
	    Issue: 31,  
	    Pages: 9832-9842 
	    
	    
	
    
 
    
         
        
            Publisher
            American Chemical Society (ACS)
        
 
         
	
         
         
         
         
         
	
         
         
         
    
         
         
         
         
         
         
         
    
        Reviewing status
        Peer reviewed
    
 
    
        Institute(s)
        Helmholtz Pioneer Campus (HPC)
    
 
     
     
     
     
     	
    
    
        PubMed ID
        26149349
    
    
        Erfassungsdatum
        2019-01-16