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Improving visibility in limited-view scenarios with dynamic particle-enhanced optoacoustic tomography.

Proc. SPIE 10064 (2017)
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Limited-view artefacts affect most optoacoustic (photoacoustic) imaging systems due to geometrical constraints that impede achieving full tomographic coverage as well as limited light penetration into scattering and absorbing objects. Indeed, it has been theoretically established and experimentally verified that accurate optoacoustic images can only be obtained if the imaged sample is fully enclosed (< π angular coverage) by the measuring locations. Since in many cases full angular coverage cannot be achieved, the visibility of structures along certain orientations is hampered. These effects are of particular relevance in the case of hand-held scanners with the imaged volume only accessible from one side. Herein, a new approach termed dynamic particle-enhanced optoacoustic tomography (DPOT) is described for accurate structural imaging in limited-view scenarios. The method is based on the non-linear combination of a sequence of tomographic reconstructions representing sparsely distributed moving particles. Good performance of the method is demonstrated in experiments consisting of dynamic visualization of flow of suspended microspheres in three-dimensions. The method is expected to be applicable for improving accuracy of angiographic optoacoustic imaging in living organisms.
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Publication type Article: Journal article
Document type Scientific Article
Keywords Limited-view Effects ; Non-linear Reconstruction ; Optoacoustic Tomography ; Photoacoustic Tomography
Language english
Publication Year 2017
HGF-reported in Year 2017
ISSN (print) / ISBN 0277-786X
e-ISSN 1996-756X
Quellenangaben Volume: 10064 Issue: , Pages: , Article Number: , Supplement: ,
Publisher SPIE
Reviewing status Peer reviewed
POF-Topic(s) 30205 - Bioengineering and Digital Health
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-505590-001
Scopus ID 85019180205
Erfassungsdatum 2019-02-15