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Mazzola, R.* ; Corradini, S.* ; Eidemüller, M. ; Figlia, V.* ; Fiorentino, A.* ; Giaj-Levra, N.* ; Nicosia, L.* ; Ricchetti, F.* ; Rigo, M.* ; Musola, M.* ; Ceccaroni, M.* ; Gori, S.* ; Magrini, S.M.* ; Alongi, F.*

Modern radiotherapy in cancer treatment during pregnancy.

Crit. Rev. Oncol. Hematol. 136, 13-19 (2019)
Postprint DOI PMC
Open Access Green
Breast cancer, gynecological malignancies and lymphomas are the most frequently diagnosed tumors in pregnant women. The feasibility of radiotherapy during pregnancy remains a subject of debate and clinicians continue to hesitate on this approach, trying to avoid radiotherapy in most cases. Since the 1990s, several technological advances, including intensity modulated and image guided radiation delivery, have been implemented in radiation oncology to improve the radiation treatment in terms of effectiveness and tolerability. It remains uncertain which short- and long-term health effects the radiation exposure of the fetus may have through advanced radiotherapy techniques. The present systematic literature review aims to summarize the limited current evidences of the feasibility and clinical results of "modern" radiotherapy procedures for the treatment of the most frequently diagnosed tumors in pregnant women.
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Publication type Article: Journal article
Document type Review
Keywords Radiotherapy ; Pregnancy ; Review ; Cancer; Exposed In-utero; Breast-conserving Surgery; Hodgkins-disease; Vivo Dosimetry; Radiation; Carcinoma; Management; Childhood; Therapy; Women
Language english
Publication Year 2019
HGF-reported in Year 2019
ISSN (print) / ISBN 1040-8428
e-ISSN 1040-8428
Journal Critical Reviews in Oncology / Hematology
Quellenangaben Volume: 136, Issue: , Pages: 13-19 Article Number: , Supplement: ,
Publisher Elsevier
Publishing Place Ste 800, 230 Park Ave, New York, Ny 10169 Usa
Reviewing status Peer reviewed
Institute(s) Institute of Radiation Medicine (IRM)
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Radiation Sciences
PSP Element(s) G-501391-001
DOI 10.1016/j.critrevonc.2019.02.002
WOS ID WOS:000463306600002
Scopus ID 85061527464
PubMed ID 30878124
Erfassungsdatum 2019-03-15
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