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Broken hearts: Iron overload, ferroptosis and cardiomyopathy.
Cell Res. 29, 263-264 (2019)
In a recently published paper in Proc Natl Acad Sci USA, Fang et al. elegantly demonstrated that doxorubicin treatment or transient ischemia/reperfusion in mice triggers ferroptosis, a distinctive form of necrotic cell death marked by irondependent lipid peroxidation, which is the main underlying mechanism in the pathogenesis of cardiomyopathy.
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Publication type
Article: Journal article
Document type
Comment, Opinion
Keywords
Cell-death
ISSN (print) / ISBN
1001-0602
e-ISSN
1748-7838
Journal
Cell Research
Quellenangaben
Volume: 29,
Issue: 4,
Pages: 263-264
Publisher
Nature Publishing Group
Publishing Place
Shanghai
Reviewing status
Peer reviewed
Institute(s)
Institute of Developmental Genetics (IDG)