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Diehl, C. ; Halasz, L.M.* ; Wilkens, J.J.* ; Grosu, A.-L.* ; Combs, S.E.

The role of particle therapy for the treatment of skull base tumors and tumors of the Central Nervous System (CNS).

Top. Magn. Reson. Imaging 28, 49-61 (2019)
Publ. Version/Full Text DOI PMC
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Radiation therapy (RT) is a mainstay in the interdisciplinary treatment of brain tumors of the skull base and brain. Technical innovations during the past 2 decades have allowed for increasingly precise treatment with better sparing of adjacent healthy tissues to prevent treatment-related side effects that influence patients' quality of life. Particle therapy with protons and charged ions offer favorable kinetics with sharp dose deposition in a well-defined depth (Bragg-Peak) and a steep radiation fall-off beyond that maximum. This review highlights the role of particle therapy in the management of primary brain tumors and tumors of the skull base.
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Publication type Article: Journal article
Document type Review
Language english
Publication Year 2019
HGF-reported in Year 2019
ISSN (print) / ISBN 0899-3459
e-ISSN 1536-1004
Quellenangaben Volume: 28, Issue: 2, Pages: 49-61 Article Number: , Supplement: ,
Publisher Lippincott Williams & Wilkins
Publishing Place Hagerstown, Md.
Reviewing status Peer reviewed
POF-Topic(s) 30203 - Molecular Targets and Therapies
Research field(s) Radiation Sciences
PSP Element(s) G-501300-001
Scopus ID 85065436898
PubMed ID 31022048
Erfassungsdatum 2019-05-13