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Tumor cell dormancy-triggered by the niche.
Dev. Cell 49, 311-312 (2019)
Publ. Version/Full Text
DOI
PMC
Dormant cancer cells often survive treatment and increase the risk for tumor relapse, associated with dismal prognosis. Two recent papers describe mechanisms used by the bone marrow niche to regulate leukemia dormancy. The findings provide a molecular basis for niche-targeting therapies that may enable elimination of dormant tumor cells.
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Publication type
Article: Journal article
Document type
Letter to the Editor
Keywords
Self-renewal; Leukemia
ISSN (print) / ISBN
1534-5807
e-ISSN
1878-1551
Journal
Developmental Cell
Quellenangaben
Volume: 49,
Issue: 3,
Pages: 311-312
Publisher
Elsevier
Publishing Place
50 Hampshire St, Floor 5, Cambridge, Ma 02139 Usa
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Research Unit Apoptosis in Hematopoietic Stem Cells (AHS)