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Kinase, S.* ; Mohammadi, A.* ; Takahashi, M.* ; Saito, K.* ; Zankl, M. ; Kramer, R.*

Computer simulations for internal dosimetry using voxel models.

Radiat. Prot. Dosim. 146, 191-194 (2011)
DOI PMC
Open Access Green as soon as Postprint is submitted to ZB.
n the Japan Atomic Energy Agency, several studies have been conducted on the use of voxel models for internal dosimetry. Absorbed fractions (AFs) and S values have been evaluated for preclinical assessments of radiopharmaceuticals using human voxel models and a mouse voxel model. Computational calibration of in vivo measurement system has been also made using Japanese and Caucasian voxel models. In addition, for radiation protection of the environment, AFs have been evaluated using a frog voxel model. Each study was performed by using Monte Carlo simulations. Consequently, it was concluded that these data of Monte Carlo simulations and voxel models could adequately reproduce measurement results. Voxel models were found to be a significant tool for internal dosimetry since the models are anatomically realistic. This fact indicates that several studies on correction of the in vivo measurement efficiency for the variability of human subjects and interspecies scaling of organ doses will succeed.
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Publication type Article: Journal article
Document type Scientific Article
Corresponding Author
Keywords Monte-Carlo-simulation; Phantoms; Adult; Mouse
ISSN (print) / ISBN 0144-8420
e-ISSN 1742-3406
Quellenangaben Volume: 146, Issue: 1-3, Pages: 191-194 Article Number: , Supplement: ,
Publisher Oxford University Press
Publishing Place Oxford
Non-patent literature Publications
Reviewing status Peer reviewed