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Open Access Green as soon as Postprint is submitted to ZB.
Genome-wide association studies of atrial fibrillation: Past, present, and future.
Cardiovasc. Res. 89, 701-709 (2011)
Genome-wide association studies (GWAS) for atrial fibrillation (AF) have identified three distinct genetic loci on chromosomes 1q21, 4q25, and 16q22 that are associated with the arrhythmia. Susceptibility loci also have been identified by GWAS for PR interval duration, a quantitative phenotype related to AF. In this review article, we have sought to summarize the latest findings for population-based genetic studies of AF, to highlight ongoing functional studies, and to explore the future directions of genetic research on AF.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
Atrial fibrillation; Genetics; Genome-wide association study; Single nucleotide polymorphism; Arrhythmia
Language
english
Publication Year
2011
HGF-reported in Year
2011
ISSN (print) / ISBN
0008-6363
e-ISSN
1755-3245
Journal
Cardiovascular Research
Quellenangaben
Volume: 89,
Issue: 4,
Pages: 701-709
Publisher
Oxford University Press
Reviewing status
Peer reviewed
Institute(s)
Institute of Human Genetics (IHG)
POF-Topic(s)
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
Research field(s)
Genetics and Epidemiology
PSP Element(s)
G-500700-001
PubMed ID
21245058
Scopus ID
79951877285
Erfassungsdatum
2011-05-16