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ProfCom: A web tool for profiling the complex functionality of gene groups identified from high-throughput data.
Nucleic Acids Res. 36, W347-W351 (2008)
ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of 'complex functions'. A 'Complex function' is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. ProfCom provides a user friendly dialog-driven web page submission available for several model organisms and supports most available gene identifiers. In addition, the web service interface allows the submission of any kind of annotation data. ProfCom is freely available at http://webclu.bio.wzw.tum.de/profcom/.
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Publication type
Article: Journal article
Document type
Scientific Article
Keywords
EXPRESSION DATA; BIOTECHNOLOGY-INFORMATION; SCALE EXPERIMENTS; NATIONAL-CENTER; ONTO-TOOLS; ANNOTATION; RESOURCE; BIOLOGY; BABELOMICS; RELEVANCE
ISSN (print) / ISBN
0305-1048
e-ISSN
1362-4962
Journal
Nucleic Acids Research
Quellenangaben
Volume: 36,
Issue: S,
Pages: W347-W351
Publisher
Oxford University Press
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Peer reviewed