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Antonov, A.V. ; Schmidt, T.* ; Wang, Y. ; Mewes, H.-W.

ProfCom: A web tool for profiling the complex functionality of gene groups identified from high-throughput data.

Nucleic Acids Res. 36, W347-W351 (2008)
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ProfCom is a web-based tool for the functional interpretation of a gene list that was identified to be related by experiments. A trait which makes ProfCom a unique tool is an ability to profile enrichments of not only available Gene Ontology (GO) terms but also of 'complex functions'. A 'Complex function' is constructed as Boolean combination of available GO terms. The complex functions inferred by ProfCom are more specific in comparison to single terms and describe more accurately the functional role of genes. ProfCom provides a user friendly dialog-driven web page submission available for several model organisms and supports most available gene identifiers. In addition, the web service interface allows the submission of any kind of annotation data. ProfCom is freely available at http://webclu.bio.wzw.tum.de/profcom/.
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Publication type Article: Journal article
Document type Scientific Article
Keywords EXPRESSION DATA; BIOTECHNOLOGY-INFORMATION; SCALE EXPERIMENTS; NATIONAL-CENTER; ONTO-TOOLS; ANNOTATION; RESOURCE; BIOLOGY; BABELOMICS; RELEVANCE
Language english
Publication Year 2008
HGF-reported in Year 0
ISSN (print) / ISBN 0305-1048
e-ISSN 1362-4962
Quellenangaben Volume: 36, Issue: S, Pages: W347-W351 Article Number: , Supplement: ,
Publisher Oxford University Press
Reviewing status Peer reviewed
POF-Topic(s) 30505 - New Technologies for Biomedical Discoveries
Research field(s) Enabling and Novel Technologies
PSP Element(s) G-503700-001
PubMed ID 18460543
Scopus ID 48449095135
Erfassungsdatum 2008-09-18