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Kleinert, M. ; Sachs, S. ; Habegger, K.M.* ; Hofmann, S.M. ; Müller, T.D.

Glucagon regulation of energy expenditure.

Int. J. Mol. Sci. 20:5407 (2019)
Publ. Version/Full Text DOI PMC
Open Access Gold
Creative Commons Lizenzvertrag
Glucagon's ability to increase energy expenditure has been known for more than 60 years, yet the mechanisms underlining glucagon's thermogenic effect still remain largely elusive. Over the last years, significant efforts were directed to unravel the physiological and cellular underpinnings of how glucagon regulates energy expenditure. In this review, we summarize the current knowledge on how glucagon regulates systems metabolism with a special emphasis on its acute and chronic thermogenic effects.
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Publication type Article: Journal article
Document type Review
Corresponding Author
Keywords Glucagon ; Obesity ; Energy Expenditure ; Fgf21 ; Brown Adipose Tissue ; Pharmacology; Brown Adipose-tissue; Stress Hormone Infusion; Receptor Antagonist; Metabolic-response; Lipolytic Hormones; Glucose-production; Injected Glucagon; High-protein; Food-intake; Growth
ISSN (print) / ISBN 1422-0067
e-ISSN 1661-6596
Quellenangaben Volume: 20, Issue: 21, Pages: , Article Number: 5407 Supplement: ,
Publisher MDPI
Publishing Place Basel
Non-patent literature Publications
Reviewing status Peer reviewed