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Open Access Green as soon as Postprint is submitted to ZB.
Non-invasive In-vivo sensing of metabolites with a novel Optoacoustic Spectroscope in the SWIR.
In: (European Conferences on Biomedical Optics, Munich, Germany). SPIE, 2019. (Proc. SPIE ; 11077)
In this work we developed a novel near-infrared two-path optoacoustic spectrometer (NiR-TAOS) that could sense OA intensity changes due to metabolite concentration changes in-vivo. The main aim of dividing the optical path in two is 1) perform real time correction of the laser emission profile of the laser source at different wavelengths and, 2) perform pulse to pulse correction to remove laser beam fluctuation and instability to increase signal to noise ratio. Signal to noise ratio improvement was significant not only at spectral peaks, but also at all other wavelengths. The system can be used for broad applications in biomedical measurements such as various metabolites in the SWIR.
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Publication type
Article: Conference contribution
Keywords
Near-infrared Two-path Oas ; Non-invasive In-vivo Sensing Of Metabolites ; Optoacoustic ; Sensitivity And Specificity Improvement
ISSN (print) / ISBN
0277-786X
e-ISSN
1996-756X
Conference Title
European Conferences on Biomedical Optics
Conference Location
Munich, Germany
Journal
Proceedings of SPIE
Quellenangaben
Volume: 11077
Publisher
SPIE
Non-patent literature
Publications
Reviewing status
Peer reviewed
Institute(s)
Institute of Biological and Medical Imaging (IBMI)